SCHEMBL7812922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20004206	0.79	ALK (0.38)	ALKALDH1A1SMN1; SMN2KMT2APARP1
	SCHEMBL20061137	0.78	S100B (0.38)	ALKHTTALDH1A1LMNAMAPT
	SCHEMBL897012	0.78	HTR2A (0.45)	ALK
	SCHEMBL897525	0.78	ALK (0.43)	ALKALDH1A1MAPTNPSR1
	SCHEMBL897548	0.77	CA9 (0.43)	ALKDHODHHTTALDH1A1LMNA
	SCHEMBL897888	0.77	TAAR1 (0.39)	ALKALDH1A1MAPTHPGDKMT2A
	SCHEMBL20061173	0.75	S100B (0.38)	ALKHTTALDH1A1LMNAMAPT
	SCHEMBL29940794	0.74	CHEK1 (0.38)	ALKALDH1A1LMNAMAPT
	SCHEMBL27087561	0.74	CHEK1 (0.38)	ALKALDH1A1LMNAMAPT
	SCHEMBL29940534	0.74	ALK (0.38)	ALKALDH1A1KMT2APOLA1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.