SCHEMBL897548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20004206	0.79	ALK (0.38)	ALKMEN1MAPK1KMT2AIDO1
	SCHEMBL897012	0.78	HTR2A (0.45)	ALKKDM4E
	SCHEMBL897525	0.78	ALK (0.43)	ALKMAPTMAPK1ALDH1A1
	SCHEMBL20061137	0.78	S100B (0.38)	HTTCHEK1ALKMAPTMAPK1
	SCHEMBL6275679	0.77	RXRA (0.47)	CA9HTTRXRADHODHMEN1
	SCHEMBL7812922	0.77	ALK (0.43)	HTTDHODHALKMAPTKMT2A
	SCHEMBL897888	0.77	TAAR1 (0.39)	ALKKDM4EMEN1MAPTMAPK1
	SCHEMBL20061173	0.75	S100B (0.38)	HTTALKMAPTKMT2ACYP3A4
	SCHEMBL29940534	0.74	ALK (0.38)	ALKKDM4EMEN1MAPK1KMT2A
	SCHEMBL29940794	0.74	CHEK1 (0.38)	CHEK1ALKKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.