Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194334 | 0.79 | ALDH1A1 (0.58) | MAPTKDM4EPOLBL3MBTL1KIF11 | |
| SCHEMBL11445153 | 0.77 | ALDH1A1 (0.59) | KDM4EADRB2LMNAMEN1KMT2A | |
| SCHEMBL7405824 | 0.76 | NR2E1 (0.61) | MAPTKDM4EADRB2DNM1LMNA | |
| SCHEMBL4231217 | 0.76 | TLR4 (0.50) | MAPTKDM4EADRB2DNM1KIF11 | |
| SCHEMBL5018077 | 0.75 | KIF11 (0.53) | MAPTKDM4EKIF11ERAP1CYP3A4 | |
| SCHEMBL3924071 | 0.75 | PARP14 (0.50) | MAPTKDM4EKIF11ERAP1PARP14 | |
| SCHEMBL15560416 | 0.74 | KIF11 (0.47) | MAPTKDM4EPOLBRECQLL3MBTL1 | |
| SCHEMBL11537835 | 0.74 | KIF11 (0.45) | MAPTKDM4EADRB2DNM1KIF11 | |
| SCHEMBL6601301 | 0.74 | PARP14 (0.51) | MAPTKDM4ERECQLKIF11ERAP1 | |
| SCHEMBL2429422 | 0.73 | PARP14 (0.51) | MAPTKDM4EKIF11LMNAPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708767-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0708767-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5541333-A | TETHERED HAPTEN INTERMEDIATES | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0708767-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5464746-A | Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives | ABBOTT LABORATORIES (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1995003296-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1995-02-02 | — | — | WO | disclosed |