Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 10/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817580 | 0.89 | RAB9A (0.58) | RAB9ARBP4ALDH1A1KMT2ANPC1 | |
| SCHEMBL7817513 | 0.88 | BCL9 (0.49) | BCL9CTNNB1RAB9APPARARBP4 | |
| SCHEMBL7804606 | 0.82 | MAPT (0.63) | RAB9AALDH1A1KMT2ANPC1 | |
| SCHEMBL7814284 | 0.81 | ALDH1A1 (0.57) | RAB9ARBP4ALDH1A1KMT2ANPC1 | |
| SCHEMBL7817510 | 0.81 | BCL9 (0.57) | BCL9CTNNB1PPARA | |
| SCHEMBL7810100 | 0.80 | BCL9 (0.56) | BCL9CTNNB1PPARAKMT2A | |
| SCHEMBL7814025 | 0.80 | HSD11B1 (0.63) | BCL9CTNNB1PPARAALDH1A1 | |
| SCHEMBL7810746 | 0.80 | BCL9 (0.56) | BCL9CTNNB1RAB9APPARAALDH1A1 | |
| SCHEMBL7813329 | 0.80 | BCL9 (0.56) | BCL9CTNNB1PPARA | |
| SCHEMBL7809954 | 0.80 | BCL9 (0.58) | BCL9CTNNB1PPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |