Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813798 | 0.89 | BCL9 (0.58) | RAB9AALDH1A1KMT2ARBP4NPC1 | |
| SCHEMBL7810069 | 0.83 | HSD11B1 (0.59) | RAB9AALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL7817791 | 0.82 | MAPT (0.61) | RAB9AALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL27508890 | 0.81 | RAB9A (0.84) | RAB9AALDH1A1KMT2ARBP4TSHR | |
| SCHEMBL7813550 | 0.80 | CYP1A2 (0.51) | ALDH1A1KMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL7810206 | 0.79 | HSD11B1 (0.54) | ALDH1A1KMT2ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL7814130 | 0.79 | LMNA (0.54) | ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL7804429 | 0.79 | HSD11B1 (0.66) | ALDH1A1SMN1; SMN2POLBLMNAHPGD | |
| SCHEMBL7804354 | 0.78 | MAPT (0.58) | RAB9AALDH1A1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7811341 | 0.78 | PARP10 (0.64) | RAB9AALDH1A1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |