Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 5/20 | 0.33 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.33 |
| ▸ | PRKCG | P05129 | 4/20 | 0.33 |
| ▸ | PRKCH | P24723 | 4/20 | 0.33 |
| ▸ | PRKCI | P41743 | 4/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASK | O14936 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826355 | 0.88 | ALDH1A1 (0.32) | IDO1STAT3MAPTPDE9A | |
| SCHEMBL7826816 | 0.87 | ALDH1A1 (0.33) | IDO1STAT3MEN1MAPTALOX15 | |
| SCHEMBL7823271 | 0.86 | ALDH1A1 (0.35) | MEN1KMT2APDE9A | |
| SCHEMBL7819614 | 0.86 | MPO (0.36) | STAT3CYP3A4RPS6KB1PDE9A | |
| SCHEMBL7821934 | 0.85 | PDE9A (0.33) | CYP3A4RPS6KB1PDE9A | |
| Trifluoroacetic Acid SCHEMBL7839584 | 0.83 | OXER1 (0.30) | MAPT | |
| Trifluoroacetic Acid SCHEMBL7838986 | 0.80 | SSTR4 (0.33) | PDE9A | |
| SCHEMBL7515273 | 0.78 | NOS1 (0.35) | IDO1PRKCBPRKCAPRKCEPRKD3 | |
| SCHEMBL7812318 | 0.75 | PRKCB (0.33) | PRKCBPRKCATP53MAPTPDE9A | |
| SCHEMBL7507536 | 0.75 | NOS1 (0.34) | IDO1PRKCBPRKCAPRKCEPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |