Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HAT1 | O14929 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 2/20 | 0.31 |
| ▸ | CBX7 | O95931 | 1/20 | 0.31 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821934 | 0.90 | PDE9A (0.33) | PDE9ACAMK2DCDK4PRKACAPRKACG | |
| SCHEMBL7819614 | 0.88 | MPO (0.36) | PDE9AKDM4ECAMK2DCDK4PDE1C | |
| SCHEMBL7826355 | 0.87 | ALDH1A1 (0.32) | ALDH1A1PDE9A | |
| SCHEMBL7826816 | 0.86 | ALDH1A1 (0.33) | ALDH1A1PDE9APOLBMEN1KMT2A | |
| SCHEMBL7819396 | 0.86 | IDO1 (0.33) | PDE9AMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7838986 | 0.84 | SSTR4 (0.33) | PDE9A | |
| Trifluoroacetic Acid SCHEMBL7839584 | 0.82 | OXER1 (0.30) | ALDH1A1 | |
| SCHEMBL7820421 | 0.81 | PDE9A (0.40) | ALDH1A1HPGDPDE9AKDM4ECDK4 | |
| SCHEMBL7812318 | 0.79 | PRKCB (0.33) | PDE9AKDM4ECDK4 | |
| Trifluoroacetic Acid SCHEMBL7828206 | 0.75 | TPSAB1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |