Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847527 | 0.86 | ADRA1A (0.36) | — | |
| SCHEMBL8817138 | 0.83 | GRM5 (0.40) | — | |
| SCHEMBL8557798 | 0.81 | KIF11 (0.36) | — | |
| SCHEMBL8555249 | 0.81 | KIF11 (0.36) | — | |
| SCHEMBL8555959 | 0.81 | KIF11 (0.34) | — | |
| SCHEMBL8556799 | 0.81 | ACHE (0.45) | — | |
| SCHEMBL8090457 | 0.81 | TBXAS1 (0.37) | — | |
| SCHEMBL7849471 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL7832157 | 0.76 | HDAC6 (0.39) | — | |
| SCHEMBL8558771 | 0.76 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880522-B1 | 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-4-ONE DERIVATIVES AMPA AND NMDA RECEPTORS ANTAGONISTS, PREPARATION THEREOF, INTERMEDIATES THEREOF AND DRUGS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2001-09-19 | — | — | EP | disclosed |
| EP-0880522-A1 | 5H,10H-IMIDAZO 1,2-a]INDENO 1,2-e]PYRAZINE-4-ONE DERIVATIVES, PREPARATION THEREOF, INTERMEDIATES THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997025328-A1 | 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-4-ONE DERIVATIVES, PREPARATION THEREOF, INTERMEDIATES THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1997-07-17 | — | — | WO | disclosed |