Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835755 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTHTTHSD17B10 | |
| SCHEMBL7819659 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTHTTHSD17B10 | |
| SCHEMBL8556799 | 0.81 | ACHE (0.45) | — | |
| SCHEMBL7820040 | 0.81 | RORC (0.31) | — | |
| SCHEMBL8012794 | 0.80 | ELANE (0.34) | ALDH1A1GAAMAPTSMN1; SMN2ADORA3 | |
| SCHEMBL8817138 | 0.79 | GRM5 (0.40) | ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL8881566 | 0.79 | ACHE (0.40) | ALDH1A1MAPTHTTHSD17B10SMN1; SMN2 | |
| SCHEMBL7834401 | 0.79 | TBXAS1 (0.36) | TBXAS1ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL7820283 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAMAPTHSD17B10ALOX15 | |
| SCHEMBL8883880 | 0.78 | RAB9A (0.39) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5902803-A | 5H,10H-imidazo 1,2-a!indeno 1,2-e!pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE-POULENC RORER S.A. (FR) | 1999-05-11 | — | — | US | disclosed |