Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820040 | 0.83 | RORC (0.31) | — | |
| SCHEMBL7848182 | 0.83 | GRM5 (0.37) | GRM5KMT2ACA12CA9MEN1 | |
| SCHEMBL7847087 | 0.80 | KMT2A (0.43) | KMT2AMEN1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL8555249 | 0.79 | KIF11 (0.36) | — | |
| SCHEMBL8557798 | 0.79 | KIF11 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL8555959 | 0.79 | KIF11 (0.34) | — | |
| SCHEMBL8556799 | 0.79 | ACHE (0.45) | — | |
| SCHEMBL8090457 | 0.79 | TBXAS1 (0.37) | ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL7832157 | 0.78 | HDAC6 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8558771 | 0.77 | KDM4E (0.40) | KMT2AMEN1KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010246-A1 | INDENO[1,2-e]PYRAZIN-4-ONES, PREPARATION THEREOF AND MEDICAMENTS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1997-03-20 | — | — | WO | disclosed |