Sugi Predict

Sugi Predict / Compounds / SCHEMBL782214

SCHEMBL782214

SCHEMBL782214

CNC(=O)c1cc(Br)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CARM1 Q86X55 1/20 0.38
▸ DHODH Q02127 2/20 0.37
▸ PDE4B Q07343 4/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TRPV1 Q8NER1 1/20 0.35
▸ STIM1 Q13586 1/20 0.34
▸ ORAI1 Q96D31 1/20 0.34
▸ OPRL1 P41146 1/20 0.34
▸ F2 P00734 1/20 0.34
▸ F10 P00742 1/20 0.34
▸ KLKB1 P03952 1/20 0.34
▸ TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15244619 0.92 PDE4B (0.40) CARM1DHODHPDE4BKDM4EMEN1
SCHEMBL10028769 0.92 CARM1 (0.39) CARM1DHODHPDE4BKDM4EMEN1
SCHEMBL10140139 0.92 CARM1 (0.38) CARM1KDM4EMEN1ALDH1A1MAPT
SCHEMBL10028765 0.92 DHODH (0.36) DHODHPDE4BKDM4EMEN1ALDH1A1
SCHEMBL31059975 0.92 F10 (0.40) CARM1DHODHPDE4BKDM4EMEN1
SCHEMBL12911856 0.91 CARM1 (0.39) CARM1DHODHPDE4BKDM4EMEN1
SCHEMBL782368 0.91 CARM1 (0.39) CARM1PDE4BKDM4EMEN1ALDH1A1
SCHEMBL25702787 0.91 TRPV1 (0.39) CARM1DHODHPDE4BKDM4EMEN1
SCHEMBL12911649 0.91 PDE4B (0.36) DHODHPDE4BKDM4EMEN1ALDH1A1
SCHEMBL782481 0.91 DHODH (0.36) CARM1DHODHPDE4BKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 — — US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 — — EP disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-20170071205-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-03-16 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
EP-2723723-B1 N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-02-01 — — EP disclosed
US-9499524-B2 Insecticidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2016-11-22 — — US disclosed
US-20070270416-A1 Active Compound Combinations Having Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-11-22 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
WO-2007068356-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2007-06-21 — — WO disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 — — WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142327-A1 Active compound combinations having insecticidal properties ACHE, ANTXR2, NANP CARM1 1638/4885DHODH 2787/4885PDE4B 66/4885
US-20170027173-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, CASP3 CARM1 3399/4885DHODH 1693/4885PDE4B 353/4885
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties ACHE, CHRM3, CHRNA2 CARM1 781/4885DHODH 3666/4885PDE4B 277/4885
US-20070270416-A1 Active Compound Combinations Having Insecticidal and Acaricidal Properties AADAC, ACAA2, AAAS CARM1 3175/4885DHODH 2064/4885PDE4B 423/4885
US-20070244073-A1 Pesticidal Mixtures ACHE, ATL3, BPHL CARM1 2197/4885DHODH 2761/4885PDE4B 365/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 CARM1 2370/4885DHODH 874/4885PDE4B 262/4885
US-20170071205-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 CARM1 2370/4885DHODH 874/4885PDE4B 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.