Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982735 | 0.81 | CCNT1 (0.41) | CAMK2DCTSLCTSSCTSKMAPT | |
| SCHEMBL7820421 | 0.73 | PDE9A (0.40) | MAPTKMT2AMEN1PDE9AALDH1A1 | |
| SCHEMBL3337275 | 0.64 | CHRM2 (0.49) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7819995 | 0.62 | CCR6 (0.43) | CAMK2DMAPTKMT2AMEN1PDE9A | |
| SCHEMBL7005341 | 0.62 | PIM1 (0.45) | CAMK2DSCN4ASCN3AL3MBTL1 | |
| SCHEMBL8140208 | 0.61 | IMPDH2 (0.40) | MAPTKMT2AMEN1ALDH1A1MGAM | |
| SCHEMBL7819647 | 0.61 | ADORA3 (0.44) | MAPTKMT2AMEN1ALDH1A1MGAM | |
| SCHEMBL7823271 | 0.61 | ALDH1A1 (0.35) | CAMK2DPOLBKMT2AMEN1PDE9A | |
| SCHEMBL16156599 | 0.60 | CHRM2 (0.44) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7819614 | 0.60 | MPO (0.36) | CAMK2DCTSKPDE9AHTTPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |