Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TLR4 | O00206 | 3/20 | 0.34 |
| ▸ | TLR2 | O60603 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211037 | 0.90 | PPARG (0.32) | PPARGALDH1A1LMNATLR4TLR2 | |
| SCHEMBL10408167 | 0.81 | LMNA (0.37) | ALDH1A1LMNATLR4TLR2HTT | |
| SCHEMBL9561569 | 0.80 | PPARG (0.49) | PPARGALDH1A1HTTPPARAMAPT | |
| SCHEMBL17626964 | 0.75 | ALOX5 (0.34) | ALDH1A1LMNATLR4TLR2HTT | |
| SCHEMBL7823975 | 0.73 | FBP1 (0.39) | PPARGALDH1A1LMNATLR4TLR2 | |
| SCHEMBL3043526 | 0.72 | TLR4 (0.37) | PPARGALDH1A1LMNATLR4TLR2 | |
| SCHEMBL7119237 | 0.72 | ALDH1A1 (0.35) | PPARGALDH1A1LMNATLR4TLR2 | |
| SCHEMBL3081094 | 0.71 | LTA4H (0.40) | PPARGLMNAPPARARIPK1 | |
| SCHEMBL10950133 | 0.71 | TAAR1 (0.48) | ALDH1A1LMNAHTTMAPT | |
| SCHEMBL9768400 | 0.71 | CYP2C19 (0.48) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097918-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED-2-NITRO-FLUOROBENZENES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |