Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 6/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825211 | 0.87 | ITGB3 (0.51) | PRSS1 | |
| SCHEMBL8791368 | 0.85 | CHRM4 (0.44) | CCR1YAP1CHRM4CCR3PRSS1 | |
| SCHEMBL7833800 | 0.85 | YAP1 (0.44) | YAP1CHRM4CCR3PRSS1CTSG | |
| SCHEMBL7836339 | 0.85 | YAP1 (0.44) | YAP1CHRM4CCR3PRSS1CTSG | |
| SCHEMBL7833534 | 0.84 | YAP1 (0.43) | CCR1YAP1CHRM4CCR3PRSS1 | |
| SCHEMBL7833217 | 0.81 | GRIN2B (0.42) | YAP1CHRM4CCR3PRSS1CTSG | |
| SCHEMBL7835970 | 0.81 | YAP1 (0.41) | CCR1YAP1CHRM4CCR3PRSS1 | |
| SCHEMBL7835873 | 0.81 | YAP1 (0.41) | YAP1CHRM4CCR3PRSS1CTSG | |
| SCHEMBL7825685 | 0.81 | YAP1 (0.45) | YAP1HTTSIGMAR1KDM4EPKM | |
| SCHEMBL7357897 | 0.81 | YAP1 (0.46) | YAP1CHRM4CCR3PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |