SCHEMBL782485

SCHEMBL782485

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl

nearest known ligand 0.83

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 5/20 0.39
DHODH Q02127 1/20 0.37
F10 P00742 1/20 0.35
NTRK1 P04629 5/20 0.35
TRPV1 Q8NER1 1/20 0.34
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
DRD4 P21917 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM4 Q14833 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10140188 0.93 RAB9A (0.38) MALT1F10NTRK1TRPV1NPC1
SCHEMBL12528142 0.92 KMT2A (0.40) MALT1DHODHF10NTRK1MEN1
SCHEMBL782242 0.92 MALT1 (0.38) MALT1DHODHNTRK1TRPV1KMT2A
SCHEMBL13208803 0.91 MALT1 (0.39) MALT1DHODHF10TRPV1NPC1
SCHEMBL782374 0.91 DHODH (0.39) MALT1DHODHNTRK1MEN1KMT2A
SCHEMBL12935740 0.91 MALT1 (0.38) MALT1DHODHF10NTRK1TRPV1
SCHEMBL12528554 0.91 MALT1 (0.38) MALT1DHODHF10NTRK1TRPV1
Chlorantraniliprole SCHEMBL29551 0.91 DHODH (0.44) MALT1DHODHF10NTRK1TRPV1
SCHEMBL14405305 0.91 DHODH (0.36) MALT1DHODHNTRK1GRM4
Chlorantraniliprole SCHEMBL29363261 0.91 DHODH (0.44) MALT1DHODHF10NTRK1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149098-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LIMITED (IN) 2022-07-14 WO disclosed
US-20210378242-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2021-12-09 US disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 EP disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 US disclosed
US-20170071205-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-03-16 US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 US disclosed
US-7232836-B2 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-19 US disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 WO disclosed
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds E. I. DU PONT DE NEMOURS AND COMPANY 2005-04-07 US disclosed
US-20040209923-A1 Anthranilamide arthropodicide treatment FMC CORPORATION 2004-10-21 US disclosed
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides FMC CORPORATION 2004-10-07 US disclosed
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
EP-1416797-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2003015519-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210378242-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 MALT1 1035/4885DHODH 874/4885F10 2320/4885
US-20170027173-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, CASP3 MALT1 3632/4885DHODH 1693/4885F10 4090/4885
US-20040209923-A1 Anthranilamide arthropodicide treatment ANTXR2, ARF5, NPM1 MALT1 2908/4885DHODH 1442/4885F10 446/4885
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides CYP4B1, CYP1B1, CYP2E1 MALT1 3253/4885DHODH 2558/4885F10 1568/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 MALT1 1035/4885DHODH 874/4885F10 2320/4885
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds ANTXR2, HRH4, HDAC10 MALT1 1220/4885DHODH 1353/4885F10 520/4885
US-20170071205-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 MALT1 1035/4885DHODH 874/4885F10 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.