Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140154 | 0.94 | SORT1 (0.39) | DHODHLMNAMAPTSORT1MEN1 | |
| SCHEMBL782370 | 0.93 | DHODH (0.44) | DHODHMALT1LMNAMAPTSORT1 | |
| SCHEMBL30058805 | 0.93 | DHODH (0.44) | DHODHMALT1LMNAMAPTSORT1 | |
| SCHEMBL14641200 | 0.92 | DHODH (0.41) | DHODHMALT1LMNAMAPTSORT1 | |
| SCHEMBL10028774 | 0.92 | DHODH (0.36) | DHODHMALT1LMNANTRK1MEN1 | |
| SCHEMBL782485 | 0.91 | MALT1 (0.39) | DHODHMALT1NTRK1GRM4MEN1 | |
| SCHEMBL782462 | 0.90 | DHODH (0.38) | DHODHMALT1LMNAMAPTSORT1 | |
| SCHEMBL14405305 | 0.89 | DHODH (0.36) | DHODHMALT1NTRK1GRM4 | |
| SCHEMBL782214 | 0.89 | CARM1 (0.38) | DHODHMAPTMEN1KMT2A | |
| SCHEMBL30845280 | 0.87 | KMT2A (0.36) | DHODHMALT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10405548-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION LLC (US) | 2019-09-10 | — | — | US | disclosed |
| EP-2547665-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-04 | — | — | EP | disclosed |
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| EP-2723723-B1 | N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| US-9499524-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080146552-A1 | Anthranilamide Derivatives as Insecticides | SYNGENTA CROP PROTECTION, INC. | 2008-06-19 | — | — | US | disclosed |
| US-20080146552-A1 | Anthranilamide Derivatives as Insecticides | SYNGENTA CROP PROTECTION, INC. | 2008-06-19 | — | — | US | disclosed |
| US-20070244073-A1 | Pesticidal Mixtures | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244073-A1 | Pesticidal Mixtures | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | DHODH 1693/4885MALT1 3632/4885LMNA 2062/4885 |
| US-20080146552-A1 | Anthranilamide Derivatives as Insecticides | DDT, ALDH7A1, AADAC | DHODH 235/4885MALT1 2349/4885LMNA 1566/4885 |
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | DHODH 182/4885MALT1 3368/4885LMNA 2246/4885 |
| US-20070244073-A1 | Pesticidal Mixtures | ACHE, ATL3, BPHL | DHODH 2761/4885MALT1 4817/4885LMNA 2918/4885 |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | CRY1, CRYAA, ALDH7A1 | DHODH 274/4885MALT1 3077/4885LMNA 1089/4885 |
| US-10405548-B2 | Fungicidal compositions | PIK3C3, CYP51A1, CYP1B1 | DHODH 874/4885MALT1 1035/4885LMNA 946/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | DHODH 874/4885MALT1 1035/4885LMNA 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.