SCHEMBL7828048

SCHEMBL7828048

COC1(OC)NC(=N)c2c(Cl)cccc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.33
PDK2 Q15119 1/20 0.32
GRIA1 P42261 1/20 0.30
CACNG8 Q8WXS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7826961 0.84 NLRP3 (0.32)
SCHEMBL7823198 0.81 PDK2 (0.33) PDK2
SCHEMBL11179059 0.79 CES1 (0.43) CES1GRIA1CACNG8
SCHEMBL7828883 0.77 CA2 (0.33)
SCHEMBL7816249 0.76 NSD2 (0.33) CES1
SCHEMBL7816167 0.73 MAPK1 (0.36)
SCHEMBL7831442 0.73 TDP1 (0.40)
SCHEMBL8917667 0.71 CRHBP (0.33)
SCHEMBL3129229 0.71 ALDH1A1 (0.34) PDK2
SCHEMBL8917662 0.70 CES1 (0.34) CES1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed