SCHEMBL7828883

SCHEMBL7828883

COC1(OC)NC(=N)c2c(C(C)(C)C)cccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828916 0.85 NLRP3 (0.30) CA2
SCHEMBL7823198 0.78 PDK2 (0.33)
SCHEMBL7815267 0.77 CA2 (0.33) CA2GABRA1GABRB2
SCHEMBL7825538 0.77 PDK2 (0.39) CA2
SCHEMBL8919835 0.74 CA2 (0.31) CA2
SCHEMBL8919194 0.74 DHFR (0.38)
SCHEMBL7816167 0.71 MAPK1 (0.36)
SCHEMBL7831442 0.71 TDP1 (0.40) CA2
SCHEMBL7829948 0.69 CYP1A2 (0.40)
SCHEMBL3129229 0.68 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed