Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MYB | P10242 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844408 | 0.84 | NFKB1 (0.37) | GPR84ALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL6995620 | 0.69 | GPR84 (0.38) | GPR84ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL13104722 | 0.68 | MAPT (0.39) | ALDH1A1MAPTHPGD | |
| SCHEMBL8680951 | 0.63 | PDE4D (0.43) | GPR84ALDH1A1MAPTNPSR1CA12 | |
| SCHEMBL9035829 | 0.61 | HTR2C (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL7128153 | 0.60 | PDE4D (0.40) | GPR84ALDH1A1MAPTNPSR1CA12 | |
| SCHEMBL18961300 | 0.56 | NPC1 (0.42) | ALDH1A1MAPTCA12CA1CA7 | |
| SCHEMBL26140521 | 0.56 | GPR84 (0.49) | GPR84ALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL10389477 | 0.55 | SIGMAR1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13330408 | 0.55 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117656-A1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018755-A1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |