SCHEMBL7827997

SCHEMBL7827997

C=CC(O)c1cc(OC)cc(OC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CYP1A1 P04798 3/20 0.41
CYP1B1 Q16678 3/20 0.41
TUBB4A P04350 3/20 0.37
TUBB P07437 3/20 0.37
TUBA3C P0DPH7 3/20 0.37
TUBA1B P68363 3/20 0.37
TUBA4A P68366 3/20 0.37
TUBB4B P68371 3/20 0.37
TUBB3 Q13509 3/20 0.37
TUBB2A Q13885 3/20 0.37
TUBB8 Q3ZCM7 3/20 0.37
TUBA3E Q6PEY2 3/20 0.37
TUBA1A Q71U36 3/20 0.37
TUBA1C Q9BQE3 3/20 0.37
TUBB6 Q9BUF5 3/20 0.37
TUBB2B Q9BVA1 3/20 0.37
TUBB1 Q9H4B7 3/20 0.37
ABL1 P00519 5/20 0.36
BCR P11274 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17841325 0.81 AOC3 (0.51) ALDH1A1MAPTMAPK1CYP3A4
SCHEMBL30062565 0.81 AOC3 (0.51) ALDH1A1MAPTMAPK1CYP3A4
SCHEMBL1689680 0.79 CA1 (0.46) ALDH1A1KDM4EMAPTMAPK1CYP3A4
SCHEMBL16953791 0.78 ALDH1A1 (0.50) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL24148928 0.76 TUBB4A (0.47) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14007278 0.76 TRPA1 (0.38) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL19230312 0.76 ALDH1A1 (0.37) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL17371457 0.76 TUBB4A (0.47) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1818480 0.75 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1ABL1BCR
SCHEMBL16372527 0.75 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2024-09-26 US disclosed
EP-4359375-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS McMaster University (CA) 2024-05-01 EP disclosed
WO-2022266765-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2022-12-29 WO disclosed
WO-2022266765-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2022-12-29 WO disclosed
WO-2009009597-A1 WATER SOLUBLE OLEFIN METATHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-01-15 WO disclosed
EP-1075470-A1 NOVEL ANALGESIC AND IMMUNOMODULATORY CANNABINOIDS THE UNIVERSITY OF CONNECTICUT (US) 2001-02-14 EP disclosed
WO-1999057106-A1 NOVEL ANALGESIC AND IMMUNOMODULATORY CANNABINOIDS THE UNIVERSITY OF CONNECTICUT (US) 1999-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS ADH1A, AHR, ADH1C ALDH1A1 72/4885CYP1A1 34/4885CYP1B1 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.