SCHEMBL1689680

SCHEMBL1689680

C=CC(O)c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
AOC3 Q16853 2/20 0.46
HRH3 Q9Y5N1 1/20 0.45
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 3/20 0.44
ALOX15 P16050 3/20 0.44
ALOX12 P18054 2/20 0.44
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29059744 0.80 ALDH1A1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL15974748 0.79 FFAR1 (0.46) CYP2C19FFAR1
SCHEMBL15974749 0.79 FFAR1 (0.46) CYP2C19FFAR1
SCHEMBL2591240 0.79 ALDH1A1 (0.48) CA1CA2CA12CA7CA9
SCHEMBL7827997 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4MAPK1MAPTKDM4E
SCHEMBL29085806 0.78 MEN1 (0.53) CA1CA2CA12CA7CA9
SCHEMBL30062565 0.77 AOC3 (0.51) CA1CA2CA7CA9AOC3
SCHEMBL17841325 0.77 AOC3 (0.51) CA1CA2CA7CA9AOC3
SCHEMBL18253186 0.77 CA1 (0.48) CA1CA2CA12CA7CA9
SCHEMBL8025197 0.76 AOC3 (0.43) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-113548965-B Preparation method of 1,4 eneyne compound 南京工业大学 2022-07-26 CN claimed
CN-113548965-A Preparation method of 1, 4-eneyne compound 南京工业大学 2021-10-26 CN claimed
US-20260118258-A1 VALIDATION OF NATURAL MATRICES FOR THERAPEUTIC USE BIOS THERAPY PHYSIOLOGICAL SYSTEMS FOR HEALTH S P A (IT) 2026-04-30 US disclosed
US-12546707-B2 Validation of natural matrices for therapeutic use Bios-Therapy, PhysiologicalSystems for Health S.p.A. (IT) 2026-02-10 US disclosed
US-20250383343-A1 METHODS FOR DETERMINING WHEN A NATURAL THERAPEUTIC OR BENEFICIAL PRODUCT EXERTS ITS THERAPEUTIC OR BENEFICIAL EFFECT THROUGH A PHYSIOLOGICAL MODE OF ACTION BIOS-THERAPY, PHYSIOLOGICAL SYSTEMS FOR HEALTH S.P.A. (IT) 2025-12-18 US disclosed
US-20250383340-A1 METHODS FOR DETERMINING WHEN A NATURAL THERAPEUTIC OR BENEFICIAL PRODUCT EXERTS ITS THERAPEUTIC OR BENEFICIAL EFFECT THROUGH A PHYSIOLOGICAL MODE OF ACTION BIOS-THERAPY, PHYSIOLOGICAL SYSTEMS FOR HEALTH S.P.A. (IT) 2025-12-18 US disclosed
US-20250383341-A1 METHODS FOR DETERMINING WHEN A NATURAL THERAPEUTIC OR BENEFICIAL PRODUCT EXERTS ITS THERAPEUTIC OR BENEFICIAL EFFECT THROUGH A PHYSIOLOGICAL MODE OF ACTION BIOS-THERAPY, PHYSIOLOGICAL SYSTEMS FOR HEALTH S.P.A. (IT) 2025-12-18 US disclosed
US-20250231101-A1 VALIDATION OF NATURAL MATRICES FOR THERAPEUTIC USE ON HUMANS, ANIMALS AND PLANTS ON BIO-PHYSICAL BASES AS AN ALTERNATIVE TO VALIDATION THROUGH CHEMICALLY DEFINABLE SUBSTANCES DERIVED FROM SAID MATRICES BY ISOLATION AND/OR SYNTHESIS PROCESSES AND ALSO AS AN ALTERNATIVE TO PRODUCTS COMPRISING NATURAL MATRICES VALIDATED ON THE BASIS OF THEIR TRADITIONAL USE BIOS-THERAPY, PHYSIOLOGICAL SYSTEMS FOR HEALTH S.P.A. (IT) 2025-07-17 US disclosed
WO-2025149788-A1 METHODS FOR DETERMINING WHEN A NATURAL THERAPEUTIC OR BENEFICIAL PRODUCT EXERTS ITS THERAPEUTIC OR BENEFICIAL EFFECT THROUGH A PHYSIOLOGICAL MODE OF ACTION BIOS-THERAPY, PHYSIOLOGICAL SYSTEMS FOR HEALTH S.P.A. (IT) 2025-07-17 WO disclosed
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2024-09-26 US disclosed
US-20060014956-A1 Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts BRANDEIS UNIVERSITY 2006-01-19 US disclosed
WO-2005095629-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS BY MEANS OF AZEOTROPICALLY DRIED ENZYME COMPOSITIONS DSM IP ASSETS B.V. (NL) 2005-10-13 WO disclosed
WO-2005014509-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM IP ASSETS B.V. (NL) 2005-02-17 WO disclosed
US-6841691-B2 Process for the preparation of enantiomerically enriched esters and alcohols DSM N.V. (NL) 2005-01-11 US disclosed
US-20040077059-A1 Process for the preparation of enantiomerically enriched esters and alcohols DSM IP ASSETS B.V. (NL) 2004-04-22 US disclosed
EP-1283898-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM N.V. (NL) 2003-02-19 EP disclosed
WO-2001090396-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM N.V. (NL) 2001-11-29 WO disclosed
US-4014899-A ANTIASTHMATIC AND ANTIALLERGIC AGENTS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3973030-A Antiasthmatic 5,6-benzoisoindoline compositions CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS ADH1A, AHR, ADH1C CA1 2124/4885CA2 3452/4885CA12 3494/4885
US-12546707-B2 Validation of natural matrices for therapeutic use COL2A1, IL1B, COL1A1 CA1 636/4885CA2 1158/4885CA12 508/4885
US-20260118258-A1 VALIDATION OF NATURAL MATRICES FOR THERAPEUTIC USE SOST, FABP4, COL2A1 CA1 4754/4885CA2 4712/4885CA12 4474/4885
US-20060014956-A1 Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts ALDH3A1, NQO1, DERA CA1 1449/4885CA2 1014/4885CA12 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.