SCHEMBL8917662

SCHEMBL8917662

N=C1NC2(OCCO2)c2cccc(Cl)c21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.34
PDE7A Q13946 1/20 0.31
PDE7B Q9NP56 1/20 0.31
TGM2 P21980 1/20 0.31
PDK2 Q15119 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917667 0.78 CRHBP (0.33)
SCHEMBL8919799 0.75 NSD2 (0.35) CES1PDE7ATGM2
SCHEMBL8919166 0.74 PDK2 (0.39) PDK2
SCHEMBL8917731 0.74 SLC6A2 (0.34)
SCHEMBL7828048 0.70 CES1 (0.33) CES1PDK2
SCHEMBL8920969 0.68 AKR1A1 (0.37) CES1PDE7APDK2AKR1C3
SCHEMBL7826961 0.66 NLRP3 (0.32)
SCHEMBL8922231 0.61 KMT2A (0.33) PDK2
SCHEMBL8920309 0.61 PARP1 (0.35) PDK2
SCHEMBL7828007 0.60 CES1 (0.38) CES1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed