Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827728 | 0.80 | EDNRB (0.42) | EDNRA | |
| SCHEMBL7828475 | 0.80 | EDNRA (0.40) | EDNRA | |
| SCHEMBL7817685 | 0.76 | EDNRA (0.37) | EDNRA | |
| SCHEMBL7338776 | 0.75 | EDNRA (0.41) | EDNRA | |
| SCHEMBL7826340 | 0.74 | EDNRB (0.42) | EDNRA | |
| SCHEMBL7829083 | 0.71 | POLB (0.42) | EDNRA | |
| SCHEMBL7337195 | 0.71 | EDNRA (0.42) | HSD11B1EDNRA | |
| SCHEMBL7822983 | 0.70 | EDNRA (0.41) | HSD11B1EDNRA | |
| SCHEMBL7831316 | 0.70 | EDNRA (0.37) | EDNRA | |
| SCHEMBL7337701 | 0.69 | EDNRA (0.41) | EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-B1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER LAMBERT CO (US) | 2001-10-31 | — | — | EP | claimed |