SCHEMBL9162985

SCHEMBL9162985

O=C(CS)Oc1cc(Cl)ccc1Cl.[NaH]

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.41
F2 P00734 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
TP53 P04637 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
LMNA P02545 1/20 0.39
NOS2 P35228 1/20 0.39
POLB P06746 2/20 0.39
GAA P10253 1/20 0.39
RHEB Q15382 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828574 0.98 ALDH1A1 (0.44) ALDH1A1KDM4EMRGPRX4F2TDP1
SCHEMBL9159636 0.84 TDP1 (0.53) ALDH1A1MRGPRX4TDP1HTTMEN1
SCHEMBL11091005 0.81 ACHE (0.45) ALDH1A1KDM4EMRGPRX4TDP1TP53
SCHEMBL11343615 0.81 ALDH1A1 (0.50) ALDH1A1KDM4EMRGPRX4F2TDP1
SCHEMBL11093890 0.80 MEN1 (0.49) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL28781871 0.78 ALDH1A1 (0.44) ALDH1A1KDM4EMRGPRX4F2TDP1
SCHEMBL11601543 0.78 LMNA (0.49) ALDH1A1TDP1HTTKMT2ALMNA
SCHEMBL10779004 0.78 CYP1A2 (0.55) ALDH1A1KDM4EMRGPRX4TDP1HTT
SCHEMBL11221532 0.78 ALDH1A1 (0.48) ALDH1A1KDM4EMRGPRX4TDP1HTT
SCHEMBL11091140 0.77 PTK2B (0.45) TDP1HTTMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488237-B1 Method for producing dichlorophenylthioglycolic acid SUMITOMO SEIKA CHEMICALS (JP) 1995-03-01 EP disclosed
US-5210291-A METHOD FOR PRODUCING DICHLOROPHENYLTHIOGLYCOLIC ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-05-11 US disclosed
EP-0488237-A1 Method for producing dichlorophenylthioglycolic acid SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1992-06-03 EP disclosed