Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512748 | 0.83 | AKR1C3 (0.57) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL7734844 | 0.83 | KDM4E (0.51) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL7734107 | 0.81 | ICMT (0.50) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL20935020 | 0.81 | CDK2 (0.52) | LMNARXFP1TP53KDM4EHPGD | |
| Cadaverine Tartrate SCHEMBL3703327 | 0.80 | LMNA (0.45) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL7723955 | 0.80 | KDM4E (0.48) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL5241306 | 0.80 | ADRB2 (0.54) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL28991551 | 0.80 | KDM4E (0.67) | LMNARXFP1TP53KDM4EHPGD | |
| SCHEMBL20242604 | 0.80 | MTNR1A (0.56) | LMNARXFP1TP53KDM4EALDH1A1 | |
| SCHEMBL21614279 | 0.80 | KDM4E (0.50) | LMNARXFP1TP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |