Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.46 |
| ▸ | PTPRF | P10586 | 8/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69699 | 0.84 | NR4A1 (0.54) | PTPN1PTPRFPTPN2GPR35CYSLTR1 | |
| SCHEMBL4160534 | 0.79 | LMNA (0.39) | NR4A2ALDH1A1LMNAHPGD | |
| SCHEMBL10949915 | 0.78 | NR4A1 (0.47) | PTPN1PTPRFPTPN2GPR35CYSLTR1 | |
| SCHEMBL11797746 | 0.75 | TTR (0.51) | GPR35CYSLTR1NR4A1NR4A2NR4A3 | |
| SCHEMBL783749 | 0.73 | NR4A1 (0.50) | PTPN1PTPRFPTPN2GPR35CYSLTR1 | |
| SCHEMBL20793652 | 0.70 | GPR35 (0.51) | GPR35NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL5577100 | 0.70 | NAPRT (0.50) | GPR35CYSLTR1NR4A1NR4A2NR4A3 | |
| SCHEMBL11554090 | 0.70 | PTPN1 (0.60) | PTPN1PTPRFPTPN2ALDH1A1HPGD | |
| SCHEMBL5323836 | 0.69 | PTPRF (0.50) | PTPN1PTPRFPTPN2GPR35ALDH1A1 | |
| SCHEMBL9450964 | 0.69 | MEN1 (0.47) | PTPN1PTPRFPTPN2GPR35CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |