Sugi Predict

Sugi Predict / Compounds / SCHEMBL69699

SCHEMBL69699

SCHEMBL69699

O=C(O)c1cccc2c1oc1c(C(=O)O)cccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 0.54
▸ NR4A2 P43354 1/20 0.54
▸ NR4A3 Q92570 1/20 0.54
▸ ALDH1A1 P00352 3/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ DHODH Q02127 1/20 0.50
▸ GPR35 Q9HC97 1/20 0.48
▸ CYSLTR1 Q9Y271 1/20 0.48
▸ CDC25B P30305 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.43
▸ TSHR P16473 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ HPGD P15428 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ PTPRF P10586 4/20 0.43
▸ PTPN2 P17706 4/20 0.43
▸ PTPN1 P18031 4/20 0.43
▸ PRNP P04156 1/20 0.43
▸ TYMS P04818 1/20 0.43
▸ MCL1 Q07820 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10949915 0.92 NR4A1 (0.47) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL11797746 0.90 TTR (0.51) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL783749 0.86 NR4A1 (0.50) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL7829853 0.84 PTPN1 (0.46) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL5577100 0.83 NAPRT (0.50) NR4A1NR4A2NR4A3ALDH1A1DHODH
SCHEMBL7823254 0.81 MCL1 (0.51) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL11841850 0.80 ALDH1A1 (0.43) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL10949940 0.79 HSD17B10 (0.50) NR4A1NR4A2NR4A3ALDH1A1ALOX15
SCHEMBL11554090 0.79 PTPN1 (0.60) ALDH1A1KDM4EHPGDPTPRFPTPN2
SCHEMBL9450964 0.78 MEN1 (0.47) NR4A1NR4A2NR4A3GPR35CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10159738-B2 Organic-inorganic hybrid solid having a modified outer surface CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2018-12-25 — — US claimed
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-12-06 — — US claimed
EP-2855490-B1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENT (C N R S ) (FR) 2018-03-07 — — EP claimed
US-20150150981-A1 ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2015-06-04 — — US claimed
EP-2193136-B1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NAT RECH SCIENT (FR) 2014-07-30 — — EP claimed
EP-2193137-B1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NAT RECH SCIENT (FR) 2013-07-10 — — EP claimed
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS- (FR) 2010-09-09 — — US claimed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 — — US claimed
EP-2193136-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE Centre National De La Recherche Scientifique-CNRS (FR) 2010-06-09 — — EP claimed
EP-2193137-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES Centre National De La Recherche Scientifique-CNRS (FR) 2010-06-09 — — EP claimed
WO-2009077671-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2009-06-25 — — WO claimed
WO-2009077670-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2009-06-25 — — WO claimed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 — — EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 — — US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 — — US disclosed
US-20050261365-A1 Transthyretin stabilization THE SCRIPPS RESEARCH INSTITUTE (US) 2005-11-24 — — US disclosed
US-20040124399-A1 Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures MERCK PATENT GMBH (DE) 2004-07-01 — — US disclosed
US-4146624-A METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN RICHARDSON-MERRELL INC. (US) 1979-03-27 — — US disclosed
US-3953602-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10159738-B2 Organic-inorganic hybrid solid having a modified outer surface SLCO4C1, SLCO2A1, SLCO1A2 NR4A1 4358/4885NR4A2 2436/4885NR4A3 2808/4885
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE SLCO2A1, SLCO4C1, SLCO2B1 NR4A1 3589/4885NR4A2 2551/4885NR4A3 2344/4885
US-20150150981-A1 ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE SLCO4C1, SLCO2A1, SLCO1A2 NR4A1 4358/4885NR4A2 2436/4885NR4A3 2808/4885
US-20040124399-A1 Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures AFF1, AFF2, FLI1 NR4A1 902/4885NR4A2 1787/4885NR4A3 2159/4885
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 NR4A1 3569/4885NR4A2 2496/4885NR4A3 495/4885
US-20050261365-A1 Transthyretin stabilization TTR, TTPA, ALB NR4A1 2206/4885NR4A2 2098/4885NR4A3 1861/4885
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 NR4A1 3557/4885NR4A2 2474/4885NR4A3 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.