Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 5/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382080 | 0.88 | MAOA (0.63) | ALDH1A1KDM4EMAOBMAOATBK1 | |
| SCHEMBL18854814 | 0.86 | ALOX5 (0.55) | NR4A1NR4A2NR4A3ALOX5KDM4E | |
| SCHEMBL69699 | 0.86 | NR4A1 (0.54) | NR4A1NR4A2NR4A3DHODHPTPRF | |
| SCHEMBL22645256 | 0.84 | MAPT (0.51) | ALOX5PTPN1ALDH1A1MAOBMAOA | |
| SCHEMBL4586057 | 0.84 | ALOX5 (0.48) | ALOX5ALDH1A1ALOX15KDM4EMAOA | |
| SCHEMBL28084237 | 0.84 | ALDH1A1 (0.59) | ALOX5ALDH1A1KDM4EUSP2CSNK2A2 | |
| SCHEMBL14825579 | 0.84 | ALOX5 (0.48) | ALOX5ALDH1A1KDM4EMAOBMAOA | |
| SCHEMBL20793652 | 0.83 | GPR35 (0.51) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL10949940 | 0.82 | HSD17B10 (0.50) | NR4A1NR4A2NR4A3DHODHPTPRF | |
| SCHEMBL11554090 | 0.82 | PTPN1 (0.60) | PTPRFPTPN2PTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550587-A1 | STEREOSELECTIVE PREPARATION OF ACID SENSITIVE AMIDES AND INTERMEDIATES USEFUL IN SAID PREPARATION | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992005146-A1 | STEREOSELECTIVE PREPARATION OF ACID SENSITIVE AMIDES AND INTERMEDIATES USEFUL IN SAID PREPARATION | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-04-02 | — | — | WO | claimed |
| US-5086179-A | Process for the preparation of optically pure amides | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-02-04 | — | — | US | claimed |
| JP-9263558-A | — | — | None | — | — | JP | disclosed |
| US-20250136584-A1 | Benzimidazole Or Azabenzimidazole Compound, Preparation Method Therefor And Use Thereof | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2025-05-01 | — | — | US | disclosed |
| EP-4467538-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2024-11-27 | — | — | EP | disclosed |
| CN-118955479-A | Benzimidazole or azabenzimidazole compound, preparation method and application thereof | 成都地奥九泓制药厂 | 2024-11-15 | — | — | CN | disclosed |
| CN-116574092-B | Benzimidazole or azabenzimidazole compound, preparation method and application thereof | 成都地奥九泓制药厂 | 2024-08-20 | — | — | CN | disclosed |
| US-20240224781-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-07-04 | — | — | US | disclosed |
| CN-117801022-A | Organic electroluminescent material and device | 环球展览公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023222084-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都地奥九泓制药厂 | 2023-11-23 | — | — | WO | disclosed |
| EP-0494140-A1 | DIBENZOFURANCARBOXAMIDES | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| WO-1992009592-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992005146-A1 | STEREOSELECTIVE PREPARATION OF ACID SENSITIVE AMIDES AND INTERMEDIATES USEFUL IN SAID PREPARATION | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-5086179-A | Process for the preparation of optically pure amides | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-02-04 | — | — | US | disclosed |
| WO-1991004738-A1 | DIBENZOFURANCARBOXAMIDES | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| US-4959485-A | 5-HT3 ANTAGONISTS | RORER PHARMACEUTICAL CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1989010364-A1 | DIBENZOFURANCARBOXAMIDES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0339950-A2 | Dibenzofurancarboxamides, their use as pharmaceutical agents, a composition containing the same, and a process for the preparation thereof | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| US-4863921-A | Dibenzofurancarboxamides and their pharmaceutical compositions and methods | RORER PHARMACEUTICAL CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240224781-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, LOXL1, SSB | NR4A1 751/4885NR4A2 979/4885NR4A3 1080/4885 |
| US-20250136584-A1 | Benzimidazole Or Azabenzimidazole Compound, Preparation Method Therefor And Use Thereof | GLP1R, GIPR, SLC5A1 | NR4A1 839/4885NR4A2 1965/4885NR4A3 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.