Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826292 | 0.90 | KDM4E (0.47) | DYRK1AABCG2STING1ALDH1A1KDM4E | |
| SCHEMBL7823545 | 0.86 | KMT2A (0.52) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL9216251 | 0.86 | PARP1 (0.49) | DYRK1AABCG2STING1ALDH1A1KDM4E | |
| SCHEMBL7827951 | 0.84 | DYRK1A (0.44) | DYRK1AABCG2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7827216 | 0.83 | DYRK1A (0.42) | DYRK1AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL7816523 | 0.82 | CHEK1 (0.51) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL1115295 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL7825768 | 0.81 | MAOA (0.47) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7824147 | 0.80 | KDM4E (0.40) | DYRK1AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL7831835 | 0.80 | CTSV (0.40) | ABCG2ALDH1A1KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |