Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675612 | 0.80 | NAAA (0.64) | NAAAFAAH | |
| SCHEMBL7363658 | 0.73 | GRM5 (0.38) | NAAANOTUMMAPTTHRBALDH1A1 | |
| SCHEMBL13525163 | 0.69 | NOTUM (0.69) | NOTUMMAPTCYP2C19THRBALDH1A1 | |
| SCHEMBL7694428 | 0.69 | NAAA (0.51) | NAAAMAPTFAAH | |
| SCHEMBL19543173 | 0.68 | LMNA (0.44) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL24313258 | 0.68 | POLB (0.45) | NAAAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL4398431 | 0.67 | CYP1A2 (0.36) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3851748 | 0.67 | NAAA (0.49) | NAAAFAAH | |
| SCHEMBL16335477 | 0.66 | NAAA (0.54) | NAAANOTUMMAPTFAAHCYP1A2 | |
| SCHEMBL2685170 | 0.65 | MAPT (0.50) | NOTUMMAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573667-B1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-5731431-A | Process for preparing 4-substituted azetidinone derivatives | NIPPON SODA CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0573667-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |