Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453024 | 0.88 | MMP13 (0.40) | PDE5ACNR1DAOEGFR | |
| SCHEMBL7453033 | 0.87 | CTSG (0.44) | CNR1CTSGCTRB1ROCK2ROCK1 | |
| SCHEMBL7840730 | 0.86 | CTSG (0.36) | PDE5ACNR1CTSGCTRB1ROCK2 | |
| SCHEMBL7840061 | 0.85 | TAS1R3 (0.42) | HDAC6CNR1EGFR | |
| SCHEMBL7452027 | 0.84 | PDE5A (0.41) | PDE5ACNR1CTSGCTRB1ROCK2 | |
| SCHEMBL7457472 | 0.82 | CYP4F2 (0.48) | PDE5A | |
| SCHEMBL7827408 | 0.81 | CNR1 (0.47) | CNR1 | |
| SCHEMBL7838799 | 0.71 | MTNR1A (0.41) | HDAC6ROCK2ROCK1MME | |
| SCHEMBL7837953 | 0.70 | SMN1; SMN2 (0.45) | CNR1 | |
| SCHEMBL7451211 | 0.70 | SMN1; SMN2 (0.45) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |