Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12990387 | 0.91 | ESR1 (0.39) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL12990799 | 0.91 | ESR1 (0.39) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL13039553 | 0.84 | MRGPRX4 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL13039557 | 0.83 | APP (0.37) | KDM4EMAPTMAPK1ADRA1AACHE | |
| SCHEMBL29331878 | 0.82 | PDE4D (0.33) | ESR1ESR2 | |
| SCHEMBL13039556 | 0.81 | SGPL1 (0.33) | AAK1 | |
| SCHEMBL783650 | 0.77 | ESR1 (0.35) | ESR1ESR2KDM4EAAK1 | |
| SCHEMBL25693989 | 0.77 | S1PR5 (0.35) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL25695257 | 0.76 | L3MBTL1 (0.35) | ESR1ESR2AAK1 | |
| SCHEMBL25574725 | 0.76 | L3MBTL1 (0.35) | ESR1ESR2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400561-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-07-17 | — | — | EP | disclosed |
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-11655417-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-05-23 | — | — | US | disclosed |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20150299574-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-9096795-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-9096795-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-9096795-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2432851-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-10-02 | — | — | EP | disclosed |
| EP-2432851-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-10-02 | — | — | EP | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| WO-2010133278-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133278-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-11-25 | — | — | WO | disclosed |
| US-7824745-B2 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7678929-B2 | Furochroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20090023802-A1 | Benzochromene Derivatives | MERCK PATENT GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20080177095-A1 | FUROCHROMAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177095-A1 | FUROCHROMAN DERIVATIVES | CFD, LMAN1, UROD | ESR1 2619/4885ESR2 1410/4885KDM4E 4424/4885 |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | ESR1 2530/4885ESR2 2912/4885KDM4E 3492/4885 |
| US-20090023802-A1 | Benzochromene Derivatives | SBDS, CRY1, DDT | ESR1 302/4885ESR2 742/4885KDM4E 3570/4885 |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | LPXN, VCL, ACP3 | ESR1 1013/4885ESR2 2665/4885KDM4E 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.