Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490690 | 0.94 | P2RY2 (0.40) | LMNABRD4ALDH1A1 | |
| SCHEMBL7492166 | 0.92 | LMNA (0.43) | LMNABRD4ALDH1A1 | |
| SCHEMBL7491391 | 0.84 | P2RY2 (0.39) | LMNAALDH1A1 | |
| SCHEMBL7507165 | 0.83 | LMNA (0.34) | LMNABRD4 | |
| SCHEMBL7485651 | 0.82 | P2RY2 (0.47) | LMNABRD4ALDH1A1 | |
| SCHEMBL7840949 | 0.82 | P2RY2 (0.39) | LMNAALDH1A1 | |
| SCHEMBL7488455 | 0.82 | ATAD2 (0.40) | LMNAALDH1A1 | |
| SCHEMBL7831877 | 0.79 | KMT2A (0.39) | LMNAALDH1A1 | |
| SCHEMBL7840803 | 0.76 | ATAD2 (0.38) | LMNAALDH1A1 | |
| SCHEMBL7486706 | 0.75 | P2RY2 (0.37) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984963-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-04-11 | — | — | EP | disclosed |
| US-6162808-A | Compounds | ASTRAZENECA U.K. LIMITED (GB) | 2000-12-19 | — | — | US | disclosed |