SCHEMBL7841592

SCHEMBL7841592

CCC(=S)c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 2/20 0.47
DUSP3 P51452 1/20 0.47
PTPN5 P54829 1/20 0.47
PTPN11 Q06124 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995236 0.78 ALDH1A1 (0.44) ALDH1A1MAPTHPGDHDAC3HDAC4
SCHEMBL28627352 0.76 GSK3B (0.56) ALDH1A1MAPTHPGDDUSP3PTPN5
SCHEMBL2389975 0.75 ATM (0.50) ALDH1A1MAPTHPGDHDAC3HDAC4
SCHEMBL432650 0.73 CES2 (0.44) ALDH1A1MAPTHPGDDUSP3PTPN5
SCHEMBL8995230 0.73 SMN1; SMN2 (0.59) ALDH1A1MAPTHPGDGSK3BHTT
SCHEMBL28879993 0.72 ALDH1A1 (0.48) ALDH1A1MAPTHPGDDUSP3PTPN5
SCHEMBL8394622 0.72 SMN1; SMN2 (0.58) ALDH1A1MAPTHPGDHDAC3HDAC1
SCHEMBL7214228 0.71 GSK3B (0.64) ALDH1A1MAPTHDAC3HDAC4HDAC1
SCHEMBL196299 0.71 GSK3B (0.64) ALDH1A1MAPTHDAC3HDAC4HDAC1
SCHEMBL17187853 0.71 GSK3B (0.64) ALDH1A1MAPTHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125931-A1 Biocidal alkyl-substituted-(hetero)aryl-ketoxime-O-ethers and the production method thereof Hunan Research Institute of Chemical Industry (CN) 2001-08-22 EP disclosed