Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.31 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524613 | 0.96 | — | — | |
| SCHEMBL7518405 | 0.96 | — | — | |
| SCHEMBL7526223 | 0.80 | — | — | |
| SCHEMBL7517505 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRSMN1; SMN2TP53 | |
| SCHEMBL7511568 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRSMN1; SMN2TP53 | |
| SCHEMBL5340594 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRSMN1; SMN2TP53 | |
| SCHEMBL33715 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRSMN1; SMN2TP53 | |
| SCHEMBL7515563 | 0.80 | — | — | |
| SCHEMBL13399057 | 0.79 | — | — | |
| SCHEMBL4970507 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045667-A1 | Process for preparing polyoxyalkylene glycol ethers using block polymers as demulsifiers | CLARIANT INTERNATIONAL LTD. | 2008-02-21 | — | — | US | claimed |
| US-20070149793-A1 | Heterogeneous ruthenium catalyst, nucleus-hydrogenated diglycidyl ether of bisphenols a and f, and method for the production thereof | BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) | 2007-06-28 | — | — | US | claimed |
| US-20240059838-A1 | ALKOXYLATED POLYMERIC N-(HYDROXYALKYL)AMINE AS WETTING AGENTS AND AS A COMPONENT OF DEFOAMER COMPOSITIONS | BASF SE (DE) | 2024-02-22 | — | — | US | disclosed |
| EP-4263673-A1 | ALKOXYLATED POLYMERIC N-(HYDROXYALKYL)AMINE AS WETTING AGENTS AND AS A COMPONENT OF DEFOAMER COMPOSITIONS | BASF SE (DE) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129368-A1 | ALKOXYLATED POLYMERIC N-(HYDROXYALKYL)AMINE AS WETTING AGENTS AND AS A COMPONENT OF DEFOAMER COMPOSITIONS | BASF SE (DE) | 2022-06-23 | — | — | WO | disclosed |
| WO-2018184151-A1 | Light cure epoxy composition | HENKEL AG & CO. KGAA (DE) | 2018-10-11 | — | — | WO | disclosed |
| EP-2209836-B1 | ALKOXYLATED POLYALKANOLAMINES | BASF SE (DE) | 2016-02-24 | — | — | EP | disclosed |
| CN-103111270-B | Adsorbing material of hepatitis B antigen protein and preparation method of material | WANG YEFU | 2015-06-10 | — | — | CN | disclosed |
| CN-103111270-A | Adsorbing material of hepatitis B antigen protein and preparation method thereof | WUHAN ZHENFU MEDICAL SCIENCE & TECHNOLOGY DEV CO LTD | 2013-05-22 | — | — | CN | disclosed |
| US-8129326-B2 | Alkoxylated polyalkanolamines | BASF SE (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20100234631-A1 | ALKOXYLATED POLYALKANOLAMINES | BASF SE (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-2209836-A1 | ALKOXYLATED POLYALKANOLAMINES | BASF SE (DE) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009060060-A1 | ALKOXYLATED POLYALKANOLAMINES | BASF SE (DE) | 2009-05-14 | — | — | WO | disclosed |
| CN-1687168-A | Method for preparing grouting material of modified polyacrylamide | GUANGZHOU INST CHEMISTRY CAS (CN) | 2005-10-26 | — | — | CN | disclosed |
| US-5093392-A | Paint for food and beverage containers | THE GLIDDEN COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5051470-A | Self-curing graft polymer formed by copolymerization of ethylenically unsaturated monomers in the presence of the epoxy resin and dispersion by adding an amine | THE GLIDDEN COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149793-A1 | Heterogeneous ruthenium catalyst, nucleus-hydrogenated diglycidyl ether of bisphenols a and f, and method for the production thereof | HNRNPL, HNRNPH3, HNRNPF | MEN1 2673/4885CHRM2 1714/4885CHRM5 1400/4885 |
| US-20100234631-A1 | ALKOXYLATED POLYALKANOLAMINES | PHOSPHO1, ALK, PARN | MEN1 2087/4885CHRM2 2195/4885CHRM5 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.