Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618121 | 0.81 | MAOB (0.46) | MAOBABCB1MAPTHTTSMN1; SMN2 | |
| SCHEMBL2625507 | 0.80 | L3MBTL1 (0.45) | MAOBMAPTHTTSMN1; SMN2 | |
| SCHEMBL8265170 | 0.79 | MAOB (0.48) | MAOBABCB1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8264411 | 0.79 | MAOB (0.44) | MAOBABCB1MAPTHTTSMN1; SMN2 | |
| SCHEMBL91372 | 0.78 | MAOB (0.43) | MAOBABCB1MAPTHTTSMN1; SMN2 | |
| SCHEMBL25466732 | 0.78 | NOS3 (0.39) | ABCB1HTTSMN1; SMN2 | |
| SCHEMBL8262885 | 0.76 | ENPP2 (0.47) | MAOBABCB1PDE2AENPP2APP | |
| SCHEMBL26482256 | 0.74 | TRPV3 (0.31) | — | |
| SCHEMBL25465548 | 0.74 | HTR1A (0.42) | MAPT | |
| SCHEMBL25466728 | 0.74 | CD274 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |