Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849227 | 0.76 | TRPA1 (0.33) | TRPA1GPR84 | |
| SCHEMBL7847311 | 0.72 | GPR84 (0.41) | TRPA1GPR84 | |
| SCHEMBL20145049 | 0.67 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL8555 | 0.67 | TRPA1 (0.35) | TRPA1GPR84 | |
| SCHEMBL3650633 | 0.66 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL7851348 | 0.65 | L3MBTL1 (0.35) | — | |
| SCHEMBL7852096 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL19983 | 0.63 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL29901519 | 0.63 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL433359 | 0.61 | TRPA1 (0.31) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |