Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499136 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL27499741 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL7851348 | 0.69 | L3MBTL1 (0.35) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL27366019 | 0.66 | TRPA1 (0.31) | — | |
| SCHEMBL7849227 | 0.63 | TRPA1 (0.33) | — | |
| SCHEMBL27528699 | 0.63 | TRPA1 (0.33) | — | |
| SCHEMBL7845259 | 0.63 | TRPA1 (0.33) | — | |
| SCHEMBL19279367 | 0.61 | — | — | |
| SCHEMBL140625 | 0.60 | PSIP1 (0.54) | ALDH1A1MEN1LMNAMAPTHTT | |
| Benzene SCHEMBL28057885 | 0.60 | PSIP1 (0.54) | ALDH1A1MEN1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |