Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848694 | 0.85 | LMNA (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL8187917 | 0.83 | USP2 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7846211 | 0.82 | MEN1 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL7846575 | 0.82 | HPD (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8393375 | 0.82 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL8530286 | 0.81 | GRIN1 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL7847649 | 0.81 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL7846561 | 0.81 | GRIN1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL7845907 | 0.81 | MAPT (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6088185 | 0.81 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |