Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837233 | 0.88 | MEN1 (0.35) | CNR2LMNAHTTMEN1KMT2A | |
| SCHEMBL7846878 | 0.86 | CYP1A2 (0.36) | CNR1GPR55LMNAHTTMEN1 | |
| SCHEMBL7837216 | 0.85 | CNR1 (0.34) | HDAC1HDAC6THRACNR1CNR2 | |
| SCHEMBL7849582 | 0.76 | MMP2 (0.34) | THRACNR2LMNAHTTMMP1 | |
| SCHEMBL7846237 | 0.75 | APP (0.34) | CNR1CNR2LMNAHTTMEN1 | |
| SCHEMBL7836697 | 0.75 | ALDH1A1 (0.43) | HDAC1LMNAALDH1A1MAPTNPC1 | |
| SCHEMBL7845578 | 0.74 | ACHE (0.31) | CNR2LMNAHTTMEN1KMT2A | |
| SCHEMBL7845064 | 0.74 | ALDH1A1 (0.37) | CNR1GPR55LMNAHTTMEN1 | |
| SCHEMBL7846525 | 0.73 | CNR2 (0.40) | CNR1CNR2LMNAMEN1KMT2A | |
| SCHEMBL7837573 | 0.73 | ENPP1 (0.33) | LIMK1CNR1GPR55LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1099690-A1 | MONOCYCLIC $g(b)-LACTAM COMPOUNDS AND CHYMASE INHIBITORS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |