Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855029 | 0.70 | TDP1 (0.45) | KMT2ANPC1GAARAB9AFAAH | |
| SCHEMBL7839454 | 0.67 | KMT2A (0.47) | TYMSKMT2ANPC1GAARAB9A | |
| SCHEMBL7854576 | 0.66 | L3MBTL1 (0.40) | KMT2AMAPTMEN1KDM4EGLA | |
| SCHEMBL3750334 | 0.66 | MEN1 (0.40) | KMT2ANPC1GAARAB9AALDH1A1 | |
| SCHEMBL9510677 | 0.66 | ALOX15 (0.50) | KMT2ANPC1GAARAB9AALDH1A1 | |
| SCHEMBL8109553 | 0.65 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7848844 | 0.65 | RXFP1 (0.37) | KMT2ANPC1GAARAB9AALDH1A1 | |
| SCHEMBL5608091 | 0.64 | TDP1 (0.52) | KMT2AGAAALDH1A1MAPTMEN1 | |
| SCHEMBL12794312 | 0.63 | EDNRB (0.39) | KMT2ANPC1GAARAB9AFAAH | |
| SCHEMBL453104 | 0.62 | ELANE (0.46) | RAB9AMAPTHPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140946-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035919-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-06-22 | — | — | WO | disclosed |