SCHEMBL785028

SCHEMBL785028

CC(C)(C)c1cc(COC(=O)c2ccc(O)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
LMNA P02545 2/20 0.55
MAPK1 P28482 3/20 0.53
ESR1 P03372 4/20 0.51
ESR2 Q92731 2/20 0.51
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
TSHR P16473 4/20 0.49
ALDH1A1 P00352 3/20 0.49
SLC6A2 P23975 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CHRM1 P11229 1/20 0.49
KDR P35968 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768900 0.97 KMT2A (0.54) KMT2AMEN1LMNAMAPK1ESR1
SCHEMBL12003778 0.90 KMT2A (0.58) KMT2AMEN1LMNAMAPK1ALDH1A1
SCHEMBL785266 0.87 CA12 (0.55) KMT2AMEN1LMNAMAPK1ESR1
SCHEMBL28893866 0.87 KMT2A (0.55) KMT2AMEN1LMNAMAPK1ALDH1A1
SCHEMBL11771768 0.87 RAB9A (0.49) KMT2AMEN1LMNAMAPK1TSHR
SCHEMBL12715350 0.86 KMT2A (0.44) KMT2AMEN1LMNAMAPK1ALDH1A1
SCHEMBL785161 0.85 SERPINE1 (0.58) KMT2AMEN1LMNAMAPK1ESR1
Phosphoric Acid SCHEMBL30073198 0.85 KMT2A (0.53) KMT2AMEN1LMNAMAPK1TSHR
SCHEMBL8875455 0.83 LMNA (0.61) KMT2AMEN1LMNAESR1ESR2
SCHEMBL5080279 0.81 RXRA (0.52) KMT2AMEN1LMNAALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION 2008-12-18 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007064843-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2007-06-07 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same GPX4, LPO, GPX1 KMT2A 2526/4885MEN1 1946/4885LMNA 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.