Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768900 | 0.88 | KMT2A (0.54) | ESR1LMNAGAANFKB1TDP1 | |
| SCHEMBL785266 | 0.87 | CA12 (0.55) | SERPINE1ESR1TYRLMNAXDH | |
| SCHEMBL785028 | 0.85 | KMT2A (0.60) | ESR1LMNATDP1ALDH1A1TSHR | |
| SCHEMBL11606856 | 0.84 | ALDH1A1 (0.49) | SERPINE1TYRLMNAGAAPOLB | |
| SCHEMBL12003778 | 0.84 | KMT2A (0.58) | LMNAGAATDP1ALDH1A1MEN1 | |
| SCHEMBL11771768 | 0.84 | RAB9A (0.49) | LMNAGAAKDM4ETDP1ALDH1A1 | |
| SCHEMBL11611846 | 0.82 | LMNA (0.43) | SERPINE1LMNAGAATDP1ALDH1A1 | |
| SCHEMBL28893866 | 0.81 | KMT2A (0.55) | LMNAGAATDP1ALDH1A1MEN1 | |
| SCHEMBL11608103 | 0.81 | KMT2A (0.58) | L3MBTL1LMNAGAATDP1ALDH1A1 | |
| SCHEMBL11607589 | 0.79 | MEN1 (0.49) | TYRL3MBTL1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-8481670-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481670-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080311065-A1 | Anti-oxidant macromonomers and polymers and methods of making and using the same | POLNOX CORPORATION | 2008-12-18 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| WO-2007064843-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007050991-A1 | STABILIZED POLYOLEFIN COMPOSITIONS | POLNOX CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311065-A1 | Anti-oxidant macromonomers and polymers and methods of making and using the same | GPX4, LPO, GPX1 | SERPINE1 182/4885ESR1 2326/4885TYR 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.