Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 4/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | MC5R | P33032 | 2/20 | 0.39 |
| ▸ | MC3R | P41968 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.39 |
| ▸ | CHRNG | P07510 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.39 |
| ▸ | CHRND | Q07001 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857072 | 0.95 | MMP2 (0.47) | MMP2FCER2MMEACECPA1 | |
| Trifluoroacetic Acid SCHEMBL8362584 | 0.92 | CTSS (0.48) | ACEITGB3ITGA2BPTPN1 | |
| Trifluoroacetic Acid SCHEMBL7860864 | 0.92 | ERAP2 (0.42) | MMP2FCER2ACEMC4RMC5R | |
| SCHEMBL7857045 | 0.92 | MMP2 (0.52) | MMP2FCER2MMEACECPA1 | |
| SCHEMBL7857129 | 0.87 | ERAP2 (0.46) | MMP2FCER2MC4RMC5RMC3R | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.84 | KDM4E (0.43) | MMP2FCER2LTA4HITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8169348 | 0.83 | MMP2 (0.42) | MMP2MMEMC4RMC5RMC3R | |
| Trifluoroacetic Acid SCHEMBL7860784 | 0.83 | FCER2 (0.57) | MMP2FCER2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL7857903 | 0.81 | CAPN1 (0.45) | MMP2MMP9 | |
| SCHEMBL7857954 | 0.81 | MMP2 (0.43) | MMP2LTA4HMMP9ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |