Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 3/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 2/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857045 | 0.97 | MMP2 (0.52) | MMP2FCER2MMEACECPA1 | |
| Trifluoroacetic Acid SCHEMBL7850362 | 0.95 | MMP2 (0.43) | MMP2FCER2MMEACECPA1 | |
| SCHEMBL7857129 | 0.92 | ERAP2 (0.46) | MMP2FCER2MC4RMC5RMC3R | |
| Trifluoroacetic Acid SCHEMBL8362584 | 0.88 | CTSS (0.48) | ACEITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7860864 | 0.87 | ERAP2 (0.42) | MMP2FCER2ACEMC4RMC5R | |
| SCHEMBL7857903 | 0.85 | CAPN1 (0.45) | MMP2 | |
| SCHEMBL7857954 | 0.85 | MMP2 (0.43) | MMP2LTA4HITGB3ITGA2B | |
| SCHEMBL7860801 | 0.83 | LTA4H (0.51) | MMP2FCER2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL7857847 | 0.82 | MMP2 (0.47) | MMP2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL7860804 | 0.82 | MMP2 (0.47) | MMP2FCER2LTA4HITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |