Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8169348

NCCC[C@@H](N)C(=O)N[C@@H](CS)Cc1ccccc1.O=C(O)C(F)(F)F.c1ccc2cc(Sc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.42
MC4R P32245 3/20 0.41
MC3R P41968 3/20 0.41
CTRB1 P17538 3/20 0.40
MME P08473 2/20 0.40
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
MC5R P33032 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8174490 0.94 MC4R (0.44) MMP2MC4RMC3RCTRB1MME
Trifluoroacetic Acid SCHEMBL7850362 0.83 MMP2 (0.43) MMP2MC4RMC3RMMEMC5R
Trifluoroacetic Acid SCHEMBL8163599 0.82 LTA4H (0.44) MMP2MC4RMC3RMC5R
Trifluoroacetic Acid SCHEMBL8163602 0.81 MMP2 (0.42) MMP2MC4RMC3RMC5R
Trifluoroacetic Acid SCHEMBL7860864 0.79 ERAP2 (0.42) MMP2MC4RMC3RMC5R
Trifluoroacetic Acid SCHEMBL8168893 0.79 ANPEP (0.51) MMP2
SCHEMBL7857072 0.77 MMP2 (0.47) MMP2MC4RMC3RMMEMC5R
Trifluoroacetic Acid SCHEMBL8362584 0.77 CTSS (0.48)
Trifluoroacetic Acid SCHEMBL8165236 0.77 MC4R (0.43) MMP2MC4RMC3RMC5R
Trifluoroacetic Acid SCHEMBL8165238 0.77 MC4R (0.43) MMP2MC4RMC3RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114310-A THERAPY FOR MICROBIAL INFECTIONS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-09-05 US disclosed