Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857072 | 0.97 | MMP2 (0.47) | MMP2LTA4HMC4RMC5RMC3R | |
| Trifluoroacetic Acid SCHEMBL7850362 | 0.92 | MMP2 (0.43) | MMP2LTA4HMC4RMC5RMC3R | |
| SCHEMBL7857129 | 0.88 | ERAP2 (0.46) | MMP2MC4RMC5RMC3RERAP2 | |
| SCHEMBL7857847 | 0.85 | MMP2 (0.47) | MMP2LTA4HCHRNA1CHRNGCHRNB1 | |
| Trifluoroacetic Acid SCHEMBL8362584 | 0.85 | CTSS (0.48) | ITGB3ITGA2BACE | |
| Trifluoroacetic Acid SCHEMBL7860864 | 0.84 | ERAP2 (0.42) | MMP2MC4RMC5RMC3RERAP2 | |
| SCHEMBL7859203 | 0.83 | LTA4H (0.55) | MMP2LTA4HCHRNA1CHRNGCHRNB1 | |
| SCHEMBL29616642 | 0.83 | MME (0.57) | MMP2MC4RMC5RMC3RFCER2 | |
| SCHEMBL7850357 | 0.82 | MMP2 (0.51) | MMP2LTA4HCHRNA1CHRNGCHRNB1 | |
| SCHEMBL7857903 | 0.82 | CAPN1 (0.45) | MMP2ERAP2LNPEPOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |