Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 2/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7860864 | 0.95 | ERAP2 (0.42) | ERAP2LNPEPMC4RMC5RMC3R | |
| SCHEMBL7857072 | 0.92 | MMP2 (0.47) | MC4RMC5RMC3RFCER2MMP2 | |
| SCHEMBL7857045 | 0.88 | MMP2 (0.52) | ERAP2LNPEPMC4RMC5RMC3R | |
| Trifluoroacetic Acid SCHEMBL7850362 | 0.87 | MMP2 (0.43) | MC4RMC5RMC3RFCER2MMP2 | |
| SCHEMBL7860762 | 0.82 | LNPEP (0.47) | ERAP2LNPEPMC4RMC5RMC3R | |
| SCHEMBL7857903 | 0.81 | CAPN1 (0.45) | ERAP2LNPEPMMP2OPRK1 | |
| Trifluoroacetic Acid SCHEMBL8362584 | 0.80 | CTSS (0.48) | OPRD1 | |
| SCHEMBL29406233 | 0.80 | ERAP2 (0.60) | ERAP2LNPEPCTSCMMP2OPRK1 | |
| SCHEMBL30973666 | 0.79 | ERAP2 (0.55) | ERAP2LNPEPMC4RMC5RMC3R | |
| SCHEMBL30643724 | 0.79 | ERAP2 (0.55) | ERAP2LNPEPMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |