Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207592 | 0.78 | CTSL (0.40) | MMP1MMP2MMP3RENCTSL | |
| SCHEMBL7204995 | 0.74 | MMP2 (0.50) | MMP1MMP2MMP3METAP2METAP1 | |
| SCHEMBL15259739 | 0.73 | CHRNB2 (0.36) | KIF11CTSSCTSK | |
| Hydrochloric Acid SCHEMBL7205141 | 0.73 | MMP2 (0.49) | MMP1MMP2MMP3METAP2METAP1 | |
| SCHEMBL7852251 | 0.73 | FAAH (0.39) | MMP1MMP2MMP3CTSLCTSB | |
| SCHEMBL7852245 | 0.72 | CTSS (0.52) | MMP1MMP2MMP3RENCTSS | |
| SCHEMBL7205030 | 0.71 | MMP2 (0.48) | MMP1MMP2MMP3KIF11METAP2 | |
| SCHEMBL7210238 | 0.71 | OPRK1 (0.36) | MMP1MMP2MMP3RENMETAP2 | |
| SCHEMBL7212756 | 0.70 | KLK7 (0.36) | MMP1MMP2MMP3RENMETAP2 | |
| SCHEMBL7852252 | 0.70 | OPRK1 (0.36) | MMP1MMP2MMP3RENMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180759-B1 | PREPARING AZACYCLOALKANOYLPSEUDOTETRAPEPTIDES COMPRISING COUPLING A DIPEPTIDE WITH A PSEUDODIPEPTIDE; FOR EXAMPLE, N-(N-ETHYL-N-(1-OXO-4-(4-PIPERIDINYL)BUTYL)GLYCYL)-(L)-ALPHA-ASPARTYL-3 -CYCLOHEXYL-(L)-ALANINEAMIDE; USE AS ANTICOAGULANTS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-01-30 | — | — | US | disclosed |