Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850312 | 0.90 | MMP2 (0.60) | MMP2CPB2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7850380 | 0.86 | CHRNB2 (0.58) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7857980 | 0.84 | LNPEP (0.55) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1246343 | 0.84 | LNPEP (0.55) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1244320 | 0.83 | CHRNB2 (0.55) | MMP2CPB2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7857066 | 0.81 | MMP8 (0.66) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7859178 | 0.81 | MMP8 (0.52) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7857079 | 0.81 | LNPEP (0.60) | MMP2ERAP2ERAP1LNPEP | |
| SCHEMBL30565150 | 0.81 | LNPEP (0.60) | MMP2ERAP2ERAP1LNPEP | |
| SCHEMBL18755213 | 0.80 | MMP2 (0.69) | MMP2CPB2HTR2AHRH1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |